There are no well controlled studies with HALDOL (haloperidol) in pregnant women. There are reports, however, of cases of limb malformations observed following maternal use of HALDOL along with other drugs which have suspected teratogenic potential during the first trimester of pregnancy. Causal relationships were not established in these cases. Since such experience does not exclude the possibility of fetal damage due to HALDOL, this drug should be used during pregnancy or in women likely to become pregnant only if the benefit clearly justifies a potential risk to the fetus.
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We don't usually notice delirium. Delirium usually goes unrecognized by people who are not looking for it (25% detection rate in routine practice; 64% by actively-screening research nurses; gold-standard: trained MDs). Two scales, the Confusion Assessment Method ( CAM-ICU ) and the Intensive Care Delirium Screening Checklist ( ICDSC ) are in use. CAM-ICU requires a 10-point test of attention to voice or pictures; the ICDSC seems more amenable to integration with the clinical exam and gestalt . One group found CAM-ICU better predicted outcomes from critical illness than did ICDSC. It has not been established that use of these scales results in superior detection of delirium compared to trained nurses using informal testing ( gestalt ).