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Fig 6. Changes in DHEA, DHEA-S, testosterone, dihydrotestosterone, and androstenedione after 400 mg oral DHEA in a 72 year-old man. DHEA-S, mcg/dl. All others, ng/dl. 14
(click on thumbnail for full sized image) On the other hand, when pharmacologic doses of DHEA are administered (., doses that are far in excess of those required to restore levels to those of healthy young adults), testosterone and DHT levels do increase significantly. For example, in one elderly man, to whom 400 mg of DHEA was administered, significant and rapid rises were noted in DHEA, DHEA-S , testosterone and DHT (Figure 6). 14