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Cautions
Use only in a specialized hospital with proper equipment for artificial respiration and in the presence of a specialist to conduct artificial respiration due to the impact of the drug on the respiratory muscles.
Close supervision is necessary during surgery and in the early postoperative period in order to maintain vital functions to the full recovery of muscle contractility.
The calculation should take into account the dose applied anesthetic technique, possible interactions with drugs administered before or during anesthesia, the patient’s condition and sensitivity to the drug.
cases anaphylactic and anaphylactoid reactions when used muscle relaxants are described in the medical literature. Despite the absence of such action messages Arduana, the drug can be used only under conditions that allow to proceed immediately to these states treatment.
Caution must be especially careful in applying Arduana with a history of the patient’s anaphylactic reaction caused by a muscle relaxant because of possible cross allergy .
Doses Arduana, causing muscle relaxation, does not have a significant cardiovascular effect and hardly cause bradycardia.
Application and dose m-holinoblokatorov sedation in order to be careful preliminary assessment; It should also take into account the stimulating effect by n. vagus other simultaneously used drugs and type of surgery.
In order to avoid relative overdosing and ensure proper control over the recovery of muscle activity is recommended to use the stimulator peripheral nerve fibers.
Patients with disorders of neuromuscular transmission, obesity, renal failure, liver disease and biliary tract under guidance of a history of myocardial polio, should be prescribed the drug in smaller doses.
in the case of liver disease Arduana application is possible only in cases where the risk is justified. This dose should be minimal.
Some states (hypokalemia, digitalization, gipermagniemiya, diuretics, hypocalcemia, hypoproteinemia, dehydration, acidosis, hypercapnia, cachexia, hypothermia) may contribute to lengthening or enhancing effect.
As is the case with other muscle relaxants, prior to use Arduana should normalize the electrolyte balance and acid-base status, eliminate dehydration.
Like other muscle relaxants Arduan can reduce the activated partial thromboplastin and prothrombin time.
Children aged 1 year to 14 years are less sensitive to pipekuroniya buy equipoise and duration miorelaksiruyushego effect they are shorter than in adults and children aged up to 1 year.
Efficacy and safety of use in the neonatal period have not been studied.
Myorelaxation effect in infants from 3 months. up to 1 year does not differ from that in adults.
Only use fresh solution.

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